There were no statistically significant differences between the supplement and placebo groups at the 6 months follow-up in body weight, body mass index (BMI), blood pressure, body pains and general health.
PTH concentration decreased and calcium/creatinine ratio increased in subjects who received vitamin D and Calcium together compared to those who received vitamin D alone. NCT02662491, First registered on 25 January 2016 (, Last update: 05 August 2019. Vitamin D an active hormone is essential for both bone and muscle health because of it is role in calcium and phosphorus homeostasis. Evidence also points to other health benefits of vitamin D because most cells in the human body have vitamin D receptors. This is strengthened further by the results of some observational studies which have reported increased risks of cardiovascular, malignant, and autoimmune diseases, however many recent studies did not confirm these results. Sunlight, diet, and dietary supplements are the main sources of vitamin D for humans. Other factors which may also affect vitamin D status includes skin pigmentation, age, smoking and adiposity. Low circulating vitamin D levels have recently been associated with increased obesity and associated cardiometabolic risk factors and pathologies including diabetes. In the United Arab Emirates (UAE) we have the 2nd highest rates of obesity in the World. In addition, several studies have revealed that vitamin D deficiency is highly prevalent in the UAE, Middle East and the Indian subcontinent.
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